Whether you lift your arm or think of what you wanna cook for dinner, you can be sure that neurotransmitters are involved. They mediate the interaction between two neurons and lead to the opening of ion channels. One of those neurotransmitters is acetylcholine which can transmit both excitatory and inhibitory effects. In order to close the ion channel, acetylcholine has to be degraded and thus be inactivated. This is done by an enzyme called acetylcholinesterase. The active site resembles a serine protease and constitutes of a Ser–His–Glu triad, which hydrolyses the acetyl group and splits the neurotransmitter into acetyl and choline. Blocking this crucial enzyme can lead to paralysis and even to death due to inability to control muscles involved in breathing.
PDB ID: 1CFJ
#proteins #protein #science #biology #biochemistry #biophysics #instascience #womeninscience #lifesciences #basel #acetylcholine #neuroscience #neurons #synapse
plural noun: neurons
A granular cell that transmits and receives nerve impulses to initiate or inhibit behavior.
When it comes to looking for the deepest mystery of the Universe, there is no need to look far out into space. Its location is actually very close to us, housed right inside our heads. The brain is an organ of extraordinary complexity constructed from relatively simple elements, in the same way that thousands of words, sentences, and narratives are constructed out of a few dozen letters.
It is comprised of approximately 100 billion individual nerve cells, called neurons, rivaling the number of stars in the Milky Way Galaxy. To give you an idea of how many neurons that is, if you were to count to 100 billion, second by second, you would be counting for nearly 3,000 years.
If you could stack 100 billion pieces of paper, the stack would be 5,000 miles high… which is the distance from Los Angeles to London.
A Shanghai Green Valley Pharmaceutical Co., Ltd. (Green Valley) anunciou hoje que a fase 3 de seu estudo das cápsulas oligomannurarato de sódio (GV-971) para a doença de Alzheimer leve a moderada chegou ao seu desfecho (endpoint) primário. Este teste clínico randomizado, duplo-cego e controlado por placebo da China visou avaliar a segurança e a eficácia do GV-971, uma droga oligossacarídica multialvo, em participantes do estudo com doença de Alzheimer leve a moderada (com o MEEM pontuando entre 11 e 26). No ramo do tratamento, os participantes tomaram o GV-971 em duas doses orais diárias de 450mg durante 36 semanas. O desfecho primário mostrou a mudança para melhor dos resultados da Escala de Avaliação da Doença de Alzheimer – subsescala cognitiva (ADAS-cog), após 36 semanas de tratamento com o GV-971, comparados aos do controle com placebo. Os dados demonstraram que o GV-971 significativamente melhorou a diminuição cognitiva. Da perspectiva de adventos adversos, o GV-971 demonstrou um perfil similar ao do placebo, com nenhuma alteração de imagem causada por amiloide (ARIA, em inglês) observada. #Alzheimer #demência #dementia #cognição #memória #linguagem #neurociência #neuroscience #neurologia #psiquiatria #gerontologia #geriatria #fonoaudiologia #fisioterapia #terapiaocupacional #nutrição #enfermagem #psicologia #cuidador #terapia #tratamento #comunicação #cérebro #neurônios #brain #neurons #sus #hospital #medicamentos
Çok sevdiğim bir storyteller yani masal anlatıcısı youtuber son videosunda insan beyninin ağaç kökleri gibi olduğuna değinmişti. Beynimizin içindeki sinapslar ve nöronlarn kökler gibi birbirine bağlı olduğunu dile getiriyordu.
Tabiat öyle mükemmel bir dizayn ki yeraltında gördüğünüz bu sanat eserlerini sonra gökyüzünde de görüyorsunuz ve fark ediyorsunuz ki aslında beynin kılcal damarlarına sinapslarına benzeyen kök yapısı galakside de kendisini gösteriyor, ama o kadar uzağa gitmenize gerek olmadığını dile getiriyor doğa ve diyor ki ; ben varoluştan bu yana sizlere bunu anlatmak istedim, uzaklara bakmayın bende görün sanatın en yalın halini. Dönüşümün o en saf biçimini, bunu anlatmak istedim sizlere hep nesiller boyu , bir gün görmeniz dileğiyle...
Sonra bir yaprak tanesi alıyorsunuz elinize ön yüzü gökyüzü, arkasında ise yeraltı gizli; o sözü edilen damarlarıyla, kökleriyle, sinapsları ve nöronlarıyla "fark et, gör artık beni" der gibi... #yaprak #beyin #nöron #neurons #sinaps #farket #farkındalık #objeart #kökler #roots #leaf #brain #barisozcan
Neuroplasticity through movement.
These beautiful microscopic connections between neurons are what allow our brains to perform such incredible & complex function. Focussed attention & complex movement can drive synaptogenesis at a rate of upto 1.8 million new connections /sec. That’s approx. 108 million potential new connections /min!
There are around 86 Billion neurons in the human brain & any 1 neuron can contact up to 10k postsynaptic cells. When you think about Neuroplasticity in terms of creating over 100 million new connections /min, the possibilities for changing movement and function are vast.
If you look at dancers, martial artists, gymnasts & the way their nervous systems can: coordinate movement, spontaneously judge depth & distance, achieve balance when unstable, recruit a precise amount of force as required etc. You’d see close to the highest degree of overall neuromuscular function and neurologic control. It’s no coincidence that these disciplines all move in complex ways through huge ranges, with large amounts of force & are constantly learning new patterns!
Sedentary lifestyles & moving only in habituated patterns are literally de-evolving humans at somewhere very close to the rate at which technological advancements make our lives easier. You can combat this by moving in novel complex ways, introducing play into your movement routines and just never being afraid to mix things up with something new in training! **If you do this well, you should be out of breath, losing concentration, sweating & generally experiencing fatigue in almost no time flat! Neuroplastic changes are fantastic, but they come a huge cost of oxygen & glucose 😅
#neuroplasticity #newmovement #synapse #synapses #neuron #neurons #newconnections #improvingmyself #improvingeveryday #improvinglives #changinglivesdaily #changinghabits #rom #danceforlife #gymnasts #martialartslife #balletdancer #mixitup #somethingneweveryday #amnacademy #amncoach #braintraining #pteducation #parkour #ninjawarrior #agilitytraining #coordination #motorskills #motordevelopment #neuro
The thing about #moderncities
is that they all look like ant colonies within 30 sec of taking off in a flight. The #aerialview
looked like #neurons
with the two water reservoirs forming the cell bodies and the dendrites of human colony spreading further on.
The two #lakes
in the picture are Chandola lake (front) and Kankaria lake( back)
Researchers have mapped each of the roughly 100,000 neurons in the poppy seed–size brain of an adult female fruit fly, according to a study published yesterday (July 19). Bock’s group sped up an imaging technique called serial section transmission electron microscopy to take 21 million images of thousands of different sections of the fruit fly brain. By putting together the images, the team has created an open-source database to give other laboratories the opportunity to peek into the fruit fly’s brain.
Credit for Image 1: EM reconstruction of Drosophila neurons by the Full Adult Fly Tracing Community. Visualization by
Philipp Schlegel (Drosophila Connectomics Group, Cambridge)
Credit for Image 2: Z. Zheng et al./Cell 2018
#ImageOfTheDay #ScienceIsCool #ScienceRules #ScienceArt #SciArt #Biology #Neurons #Neuroscience #FruitFly #Sciences #ScienceClass #ScienceGeek #ScienceIsFun #ScienceNerd #ScientistMagazine
Master the movements of your body to improve focus and awareness, reduce anxiety, and attain optimal brain functioning.
PC: Matt Krieg
Soñador: no dejes que te digan que tú sueño es una pérdida de tiempo, porque los sueños son nuestras realidades en espera. En los sueños plantamos las semillas de nuestro futuro. 💪🏻🧠🤓🤓🤓El día de hoy en tu planer anota tus sueños, tus metas a corto y largo plazo, ¿Quién quieres ser? ¿Qué quieres lograr? #dreamer #optimism #reality
Never underestimate the value of discomfort as a motivator to move forward. Understand your surroundings, and be aware that both, your desire for what is to come and relief from what currently is, propel you to get ahead.
Practicing gratitude can increase your serotonin and dopamine levels, and can lead to activation of similar mechanisms and pathways as antidepressant medications.
Anyone that is familiar with Hebb’s law knows that “neurons that fire together wire together”. This means that regularly practicing gratitude can actually help change your brain in a positive way!
Following on from yesterday's post about my CV. Today I am going to work hard with focus. I have 4 hours. Tip I found was work 30 mins, break 5 mins and so on. If you work a full day factor in your lunch break. Little breaks, walk around and drink something, the neurons and pathways in your brain need liquid. Lunch should be light. Some people say drink every 20mins when working or revising, taking exams. It does make a difference. Scientifically proven. This chunking way of working can apply to household tasks too. I would probably have shorter work periods. Going to tackle my wardrobe and drawers too!
#drinkwater #focus #chunking #neurons #pathwaysinthebrain #brainsneedwater #workpattern
These are quick references to more modern illustrations of neurons! Would especially love to make the left one for some cool brain specialist. 🐉🧠✨ #furhouseflash
awww, my sweet assistant. currently we are busy creating the tools for the interactive inspirational bodywork.....! which will finally see the light after 10 years of preparation and research.
You will be notified as soon as it is online! Get on the list here: http://eepurl.com/dBnzfv . link is in bio as well
#inspiration #bodywork #trainyourbrain #neurons #plasticity #mizi
Getting a balanced daily dose of neurotransmitters can keep us at the top of our game. Our brains release essential neurotransmitters when we have certain experiences. These hormones are vital for us to live in a high vibrational state. A great way to remember them is simply thinking of the acronym DOSE. 😉 👉Dopamine - The feeling we have when we achieve a goal or do some of our favorite activities and get excited. Keeping our dopamine levels high will keep us motivated and passionate for what we like to do.👉Oxytocin - This one is known as the bonding hormone. Healthy relationships, laughter, and connecting with others can stimulate this hormone.👉Serotonin - Gratefulness, self-appreciation, and a health self–esteem are a few things that can release this hormone.👉 Endorphins - It is that feeling we get when we are in a “zone” or overflowing with laughter. The barriers of pain can be pushed when experiencing endorphins.
Watch our Concussion video to learn about these nutrients and how they are transported through the brain's endothelial wall.
Art or science? Tree or neuron?
Don’t these trees from a painting by Disney background artist Eyvind Earle look like the neurons in the second picture?
The second drawing by Ramon y Cajal (who won the Nobel Prize for this work in 1906) is of Purkinje neurons which are neurons found in the cerebellum of vertebrates that regulate motor coordination.
This is what initially inspired me to write about the neuroscience of Sleeping Beauty (checkout the link in my bio!). And other people probably saw the resemblance because the many sensory branches of neurons are called dendrites which contains the Greek root “dendro” meaning tree!
#eyvindearle #sleepingbeauty #dendrite #tree #neuron #science #sciart #ramonycajal #neurons #cerebellum #aurora #briarrose #neuroscience