1,903 posts

#MuseumConfessions - Seriously, I love the smell of these tarpits specimens. Sometimes, if I’m walking by their cabinet, I’ll stop to open it to get a whiff. What’s your Museum confessions @brittandbone @michellembarboza @fossil_librarian @lady_naturalist @mary_annings_revenge @paleeoguy @a_fools_experiment @palaeo_james_rule #imweirdiknow #justsciencethings #museumlife #whenyouworkatamuseum #iceage #tarpits #fossils #thescicommunity #filipinoscientist
@verge did a great video about STEM and Sign Language!!! Check it out. #Repost @lorn3 ・・・ MY FAVORITE SIGN!#Macrophage 😍 #STEMSign #DeafScientist #ASL #VergeScience #TheSciCommunity #SciComm
Sometimes all we need is a sticker to make a bad day seem less 💩 Last year around this time... @dinjavanderhoorn let’s bring stickers back - I feel like we all deserve them!! 🧠🔬🎄🥂 #bestlabmates
Whoa! #WIP from @oddangel ! She is making some amazing artwork of our Barstow fossils for future exhibits and outreach! Can’t wait to see the final products. This piece is of a Gomphothere (top), an extinct cousin of elephants, and an extinct camel found in Barstow named Protolabis barstowensis. #paleoart #scienceillustration #camel #elephant #watercolor #painting #paleontology #museumlife #thescicommunity
🎵🎄 Luciferase, luciferase, how pretty are your colors... luciferase, luciferase, you're such a christmas-y experiment 🎄🎵 . (Please sing to the tune Of Christmas Tree 😂) . But for real though, the yellow color of luciferase assays are just like those sparkling Christmas tree lights 🎄 what better way to get into the holiday spirit?! . I'm just over a week away from beginning my little Christmas break, and I am so ready for it 😔 I feel like I've been go-go-go since the beginning of August with no true breaks 😭 but such is research life, is it not? But luckily for me, I get to do cool things like luciferase assays to cheer me up 😂 . Anywho, T-minus two days until my committee meeting, I am so ready for it to be over 😖 I've been cramming so much into my brain and rehearsing my presentation so much I'm pretty bored with it by now 😂 at least I'm feeling super prepared! . . . #thecurioussheep #science #scicomm #luciferaseassay #luciferase #holidayspirit #promega
One year ago today, and what a year it’s been. 🎓 • From graduating to starting my first proper job, moving to Liverpool, and buying my first washing machine. From admitting I wasn’t happy here, to applying to endless new jobs, numerous interviews, to preparing to move (again) back to Manchester. 🐝 I’ve blamed myself, and I’m not sure whether what’s next is better, but I guess as long as I keep moving (ha!) there’s more chance I’ll get somewhere. So here’s to new scary adventures. 💛 • 📸 @tom11072#YourAverageScientist #Scientist #MyLifeAsAScientist #ScientistLife #Microbiologist #Microbiology #WomenWhoScience #FemaleScientist #STEM #WomenInSTEM #WeAreSTEMSquad #TheSciCommunity #SciComm #IgersUK #IgersMCR #IgersLiverpool #IgersAustria #IgersGraz #Graduation #NewJob #Manchester #Liverpool #OneYearAgo #Moving #Change #TB #Throwback
✨Episode 3 of Sound Science airs Monday 17th December on @dublab radio✨ • 9 - 10 AM Los Angeles/12- 1 PM New York/5 - 6 PM London • This months show is all about the science of sleep and the underground music scenes that keep us from it -nourishing us in a different way. • I will be chatting to Dr Russel Foster, from Oxford University about the importance of sleep and whether or not we can maintain sleep health, while enjoying the rich music scenes that own the night 😴. • I’ll be paying homage to the first underground party scenes in New York. I’ll also be chatting to my dear friend Adam Cooper aka @foreignerrrrr about the tradition of the 🇹🇹 celebration Jouvert, and bringing the spirit of Jouvert to Los Angeles with his new early morning party #junkyardjouvert 🎉 • W/ music from Aleem, Larry Levan, Master C & J, Janet Jackson, A Tribe Called Quest, Greg Henderson, Theo Parrish, Skye, Mr. Fingers and so much more. 🔥🔥🔥 • #radio #podcast #npr #invisibilia #hiddenbrain #sciencevs #science #sciencecommunication #scicomm #thescicommunity #womeninstem #girlsinstem #blackwomeninstem #housemusic #sleephealth #sleepscience #losangeles #dublab #upallnight #rave #restlessnights #matthewwalker
✨Episode 3 of Sound Science airs Monday 17th December on @dublab radio✨ • 9 - 10 AM Los Angeles/12- 1 PM New York/5 - 6 PM London • This months show is all about the science of sleep and the underground music scenes that keep us from it -nourishing us in a different way. • I will be chatting to Dr Russel Foster, from Oxford University about the importance of sleep and whether or not we can maintain sleep health, while enjoying the rich music scenes that own the night 😴. • I’ll be paying homage to the first underground party scenes in New York. I’ll also be chatting to my dear friend Adam Cooper aka @foreignerrrrr about the tradition of the 🇹🇹 celebration Jouvert, and bringing the spirit of Jouvert to Los Angeles with his new early morning party #junkyardjouvert 🎉 • W/ music from Aleem, Larry Levan, Master C & J, Janet Jackson, A Tribe Called Quest, Greg Henderson, Theo Parrish, Skye, Mr. Fingers and so much more. 🔥🔥🔥 • #radio #podcast #npr #invisibilia #hiddenbrain #sciencevs #science #sciencecommunication #scicomm #thescicommunity #womeninstem #girlsinstem #blackwomeninstem #housemusic #sleephealth #sleepscience #losangeles #dublab #upallnight #rave #restlessnights #matthewwalker
"We organize events where people share their biggest professional FuckUp. Any chance you have a story?" - Irene Ingardi. . FuckUp Nights (FUN, @fuckupnights ) are exactly what their name indicates: public gatherings where people come to talk about their failures. Irene Ingardi coordinates FUN in Brussels. Let's ask her about it. . Q: Describe a typical FuckUp Night. . A: FUN typically happen in a sort of informal place, a nice outdoor gathering in the case of Mexico (the country where FUN started), in the case of Brussels a café or vibrant cultural centre. The format is quite easy to get: 3-4 people go on stage to tell the story of their biggest professional failure in 6:40 minutes and 10 images. After each talk, the audience asks questions. . Q: It seems a bit weird that people go on scene to expose their mistakes. How do you find your speakers? How is their experience afterwards of FUN? . A: Back in 2014 Kira and I were just two weirdos introducing ourselves in networking events with formulas like: “I work at Antiheroes, we organize events where people share their biggest professional FuckUp. Any chance you have a story?” It’s a bit easier now to introduce the subject, I normally target stories I’ve heard of or projects I like that could have a story, I get in touch and meet to break the failure story ice. We’ve had enthusiastic reactions after the FUN stage experience, people feeling “liberated” and enjoying the no filter discussion. . Q: Most events are based on success. What do you think that an event based on failures can bring that one on success cannot? . A: An event disclosing stories of failure triggers lots of attention and curiosity. First, speakers don’t get on stage to promote how brilliant they are but to expose some weakness or a story that often brought them “down to earth”. It rebalances a discourse of overnight success & meritocracy that is very present in Western societies and that leaves behind many shades of what it means to be human. It brings in an authentic and a more transparent conversation on the real path to reach a goal (focus on process rather than outcome) and heals some of the negative emotions that haunt us when scared to “fail".
✨[CERN] Fun fact Tuesday✨: You maybe already know that CERN accelerators are located underground, bellow the two countries - Switzerland and France. But do you know **why** the most tunnels (where accelerators are built) are bellow France? 🤔 If you answered "because it's cheaper to build accelerator bellow the grounds of France", you answered correctly.👏 However, the reason why is cheaper might surprise you. And no, it's not because everything is more expensive in Switzerland.😂 . . . The reason is that when you buy a land in France you own just certain, small number of meters bellow the ground. When you buy the land in Switzerland you own everything bellow your land all the way to the core of the Earth!!! 🤯🤯🤯 Since accelerators are built deep bellow the ground it was less expensive to build tunnels in land that does not belong to somebody and, I guess, a lot less paperwork. 😆 🔸Reminder: Application for CERN Summer School for STEM students is open. 🔸Advice: Apply! 🔸Suggestion: If you know somebody who would be interested, let them know! . . . Photo: my favorite mug I got @cern. Maybe I should soon share fun fact about the formula on the mug? 🤔😊 ————————————————— #womeninstem #instascience #physicsgirl #physics #physicsstudent #scicomm #stemstudent #phdstudent #phdlife #stem #studentlife #phd #womendoingscience #thescicommunity #shecanstem #studyphysics #summerinternship #liverpool #internship #cernfacs #sciencefacts #coolscience #funfacts #sciencenews #scienceisawesome #sunnerschool #blogerka #nauka #cern
Chestnuts roasting on an open fire… . … may be toxic if you picked the wrong type! This week’s Toxicology Tuesday: Christmas Toxins is a good reminder to choose the right kind of chestnuts to eat these holidays. There are several species of chestnuts, and most of these are safe to consume. Horse chestnuts, however, are neither true chestnuts nor safe to eat, but they look deceptively similar. The toxic effects of eating the horse chestnut (and the tree it comes from, if you’re into that) are mainly due to aescin (pictured), a triterpenoid saponin, and its glucoside aesculin, which are found in all parts of the plant. Whilst the underlying toxic mechanism of both compounds is unclear, ingestion can cause severe gastrointestinal upset. Large doses also cause classic symptoms of neurotoxicity, including convulsions, muscle paralysis, ataxia and confusion. Aescin has been demonstrated to (among other things) inhibit serotonin receptors, which may explain its toxic effects; the main role of serotonin in the body is to regulate digestion, and serotonin receptors also modulate the release of other neurotransmitters, including acetylcholine. It is postulated that alkaloids found in the plant also contribute to the toxic effects. Horse chestnut seed extract, with these toxic compounds removed, is commercially available and is used in alternative medicine as a remedy for just about everything, despite a colossal lack of evidence for its efficacy (a notable exception is the management of chronic venous insufficiency, for which there is strong evidence. This is likely due to the vasoprotective properties of both aescin and aesculin). Be sure to pick the right type of chestnuts this Christmas! . . . . . #science #stem #phdlife #lablife #pharmacology #biochemistry #phd #scientist #toxicology #womeninstem #scicomm #sciencecommunication #academia #discoverunder10k #postgrad #womeninscience #scientistsofinstagram #thescicommunity #toxicologytuesday #christmas #chestnuts #horsechestnut #toxins
Hi, my name is Tasha and I'm in my 4th year of my PhD. I'm struggling with my work at the moment, but this does not mean I'm a FAILURE. I'm still in the lab during my write up year but that does not mean I'm a FAILURE. I have data for 2 chapters but that last one I'm finding difficult, but this doesn't mean I'm a FAILURE. I feel like other people around me are finding this easier, publishing, are more successful, and are better than me BUT I AM NOT A FAILURE... anxiety and depression sucks, and even though I say this to myself all the time I find it hard to believe. . Anyone else ever feel like this, does it get better? Do we ever stop comparing ourselves to others?... 😭 unfortunately this is a 'normal' thing to feel, and often people around you still feel the same. Don't be afraid to reach out to people 🤗
Hi 😁, Jan (@jan.thphysics ) here. I’m a 1st year PhD candidate at the High Energy Physics Institute (IFAE) @uabbarcelona , doing research in theoretical particle physics and cosmology. To me, science is all about curiosity, creativity and exploration. It’s about finding the missing piece of the puzzle, it’s getting where no one else has ever been, it’s the joy of discovering some amazing new thing about the world. That’s why I find it so fascinating and stimulating, and I can say that I’m very proud of being a scientist. There’s quite a lot of topics that I find interesting in theoretical physics such as (to name a few) the quantum nature of black holes, what ‘banged’ in the Big Bang? or the AdS/CFT correspondence (you can ask me if you wanna know what it is 😉). However, I’m currently investigating oscillons. Shaped like balls, these objects are quite peculiar: they oscillate as if they were breathing and, in every one of these breaths, they exhale some of their energy until they eventually decay by radiating away all their remaining energy in a final breath. Apart from being very intriguing objects from a theoretical point of view, they are also believed to have been formed right after the Big Bang, potentially being quite relevant in helping us understand the history of our universe. I’m also passionate about spreading physics knowledge to as many people as I can, because I just find it so cool that I really feel that they’re missing out all the fun! That’s why I started my instagram page @jan.thphysics. Added to that I’m also using it to document my PhD days and to let the world know how the life of a theoretical physicist actually looks like. I was born and raised in Barcelona, where I obtained my physics bachelors degree. I then flew off to England for a year, where I completed a Masters degree at the University of Oxford and then returned back to Barcelona, where I currently live and work. When not busy with my PhD you’ll find me reading, running, cooking or just playing with my cat Sam. I appreciate quality time with friends and love traveling around the world meeting and connecting with new people.
“A university should be a place of light, of liberty and of learning” – Benjamin Disreali . As of this morning, on #Humanrightsday , Hasselt University has officially become a member of Scholars At Risk to protect the academic liberty and right of academics across the globe🌍. This by offering researchers the chance to temporarily continue their science projects at UHasselt.👍
Wrapped up my last work day for the year, now time for holiday packing 🙌
Let me introduce Wisdom, a Laysan albatross. She’s not just any ordinary bird either. she’s got some titles. 1. Oldest bird. She’s 68 years old. Even though birds can live a long time, that’s pretty old for a bird. 2. She’s just laid her 40th egg. Most albatrosses need a break between kids, but not Wisdom. She’s had 38 kids (her and her mate lost a chick in 2015) 3. Speaking of counting, USFWS estimates Wisdom may have logged 3 million miles in her lifetime! Since the circumference of the earth is roughly 25000 miles, she’s flown around the world 102 times powered by her own wings and supported by hollow bones. Bird bones are hollow...more aerodynamic that way. 4. Normally albatrosses mate for life with a pretty low divorce rate (7%). They date for about 4 years before they find the one. Dating in albatrosses is a lot of yammering,posturing, and skycalling. When they find their special one the two develop their own language of sorts. 5. Wisdom’s first ‘husband’ died. She’s with Akeakamai now. His name means lover of Wisdom. Heck yeah Wisdom’s got a lover at 68. How do you think she got that egg? Oh and they both survived a Tsunami in 2011. Wisdom helps me remember to be productive, always be willing to start over, live every day fully, travel the world, do more than anyone thinks possible (including yourself), oh and you’re never too old to have a lover! How does Wisdom inspire you? Photo credit: Madalyn Riley/USFWS Volunteer/Flickr 2018 #beyourself #havefun #birds #albatross #love #dating #relationships #startingover #mondaymotivation #scicomm #thescicommunity #wildconnection #wildlifeconservation #travel #wisdom
#accessibility in science and scicomm 🗣 What can you do to make your work and communication more accessible? Don’t worry you don’t have to learn new languages, but one way you can not only help communicate your work, but potentially help others in everyday life, is by learning a few words in your country’s sign language. ✋🏼 Such as: help, I’m hurt/injured, toilet 🚽, police👮🏼‍♀️, ambulance 🚑, hospital 🏥, hello, goodbye, please and thankyou! 👂 Some other tips for assisting Deaf or Hard Of Hearing individuals: 2. For images you post on instagram, twitter, facebook, make sure you have alt text set up for those using screen readers 3. Use a video editor which adds live captions in your videos like the one I used here (You may have also seen some of your favourite science communicators like @naomikohbelic and @science.sam using this in their stories) - I personally use clipomatic (I paid for the full version) but there are free live captioning apps available! 👀 To assist those with visual impairments: 1. Ensure your figures in reports, manuscripts and presentations are colourblind friendly 2. Use as big text as possible in your posters, presentations, and figures 3. Also include image descriptions/captions in talks/presentations. These are just some of the simple and free 💸 ways to avoid excluding people from accessing science! There has been some amazing conversations lately about how we can make science and science communication more accessible, lets keep it going! 🗣 What other ways do you know of that we can use to make science more accessible?
I had a great conversation with @teresa_ambrosio_com today about finding a good balance between creating captivating “content” and being authentic. I think Instagram is an amazing platform for creatives and businesses. The marketing potential is unreal and the ability to share incredibly creative snapshots (art) with millions of people instantly is fantastic. But not all that glitters is gold and I think you should have a discerning eye when it comes to what you’re putting on your feed 👀 I’ve unfollowed a few bikini brands recently because I felt the models and messages that they promoted were unhealthy and discriminating. I don’t feel bad unfollowing accounts that make me feel bad. Like they say in Hawaii, good vibes only ✨ - So on that note, I’m proposing that we start this week off with some positivity and self-love ❤️ I’ll start. I love the way I smile when someone makes me laugh. Your turn! . . . #selfiesunday #selflove #authenticity #instagramwoes #socialmedia #whatisreal #confidentwomen #loveyourself #curateyourownfeed #bodypositivity #supportyoursisters #loveyourfeed #supportwomen #promotediversity #liveauthentic #womenempowerment #womeninstem #thescicommunity #thestemsquad #theblondebiologist
! That is Cessna 172R . A four cylinder 160 horse power horizontally opposed engine. Cursing speed of 140 mph. Did you know that Cessna 172s were the most built than any other aircrafts. This is a single engine skyhawk first flown in 1955 . It’s one of the most successful sky machines built ! . What’s your fav machine ?and why ? Tell me in the comments section below ☺️. . . . #skyhawk #science #aircraft #aircraftscience #cessna #stem #loveflying #thescientist #lifeofascientist #scicomm #thescicommunity #airplane
This really ruddy infuriates me! When will governments face up to the fact that climate change IS happening, and that if we don’t do something NOW, then we will cause irreparable damage to our communities, our ecosystems and our planet? There is no Earth 2.0
I just learned that armadillos get an average of 18.5 hours of sleep per day. Well, learning that I can only say that this weekend my kitten and I definitely embraced the armadillo lifestyle 😂 Photo: selfie I took this morning before I went to my favorite breakfast place in Liverpool. ☺️ —————————————— #womeninstem #instascience #physicsgirl #physics #nerdgirl #womenwhoscience #girlswhoscience #phdstudent #phdlife #stem #studentlife #phd #womendoingscience #thescicommunity #shecanstem #studyphysics #womenempowerment #scienceblogger #scientistswhoselfie #scicomm #sciencefacts #coolscience #funfacts #sciencenews #scienceisawesome #blogger #blogerka #nauka #liverpoolbloggers #grayeyes
Making up for the fact I hated pink when I was younger! 💕
Hello hello! First post in what feels like forever 😂 . We put up a tree yesterday, so now it truly feels like the holidays! I can't wait to go home and experience some snow, Christmas lights just don't seem the same in Florida and on Palm trees 😞 but anywho, my preparations for my committee meeting are almost done! It's not a high pressure meeting, but since it's my first it's been difficult preparing without knowing what to expect 😮 but I'm feeling ready! . I got this awesome @lego ornament from @zymoresearch ☃️ I wasn't expecting it to come with my order, but everyone in my lab loves it 😂 sadly I couldn't put it on my tree because I left it in lab but I'll get it soon 🤷 I hope everyone has been having a lovely holiday season, and hopefully you're prepping for some time off 😝 . . . #thecurioussheep #science #scicomm #happyholidays #zymoresearch #holidaycheer #snowman #lego
#Repost @myfrogcroaked Mossy Red-eyed Frogs • • • Amphibians (frogs and salamanders) are important in many ecosystems: they prey on a wide range of insects and other small animals, and are prey themselves to many predators (snakes, mammals, birds). But because amphibians breathe and exchange important ions and biotic elements with their aquatic environment, they are vulnerable to changes in water chemistry. Amphibian chytrid fungus is one such water-borne threat. The fungus is spread through the water (or on the rubber boots of travelling scientists!), infects amphibians, and causes physical deformities in tadpoles that prevent them from surviving to adulthood. Specifically, this fungus infects the keratin in skin cells. Keratin is a protein found in hair, hooves, claws, & skin. It becomes tough and strong through Individual units of keratin bundling together. The proteins bind to one another through a series of intermolecular (between molecules) and intramolecular (within molecules) bonds. Hydrogen bonds are when a hydrogen interacts with either nitrogen, oxygen, or fluorine. These strong bonds can be both intra- and intermolecular. A second intermolecular bond is the disulfide bridge. Keratin is made up of a lot of sulfur containing amino acids (protein building blocks). These sulfurs bind easily to each other, creating a strong network of S-S bridges. The chytrid fungus is thought to increase the amount of keratin in frog skin cells, thickening its skin. This is fatal for frogs, who rely on their skin to breath and absorb important electrolytes from water. So what can be done to save these critters from the wrath of chytrid fungus? As field biologists and travelers, we can prevent the spread of chytrid between water bodies by washing our boots with soap after contact with water. But chytrid has already spread to many countries and is linked to frog population declines. @frogrescue in Honduras, the brainchild of @myfrogcroaked , takes infected young frogs from the wild, cures them and re-releases them into the wild. It's resource-intensive, but it could be a key strategy in reducing the loss of the world's frog diversity due to the chytrid pandemic.
Science Saturday's in the lab... transwell staining 😍 This is an image of the staining process I described in my migration post last week, it involves fixing the cells on the membrane, staining with a dye to visualise the cells, and a ton of washing with water!
#BrainyXmas day 7: The wonderful Mehwish, who I met at @fens_org this year! Who are you? My name is Mehwish Anwer (@sci_life_360 )and I am a neuroscientist in making 😀. I have done my MSc and MPhil in Molecular Biology. Currently, I am a Marie Curie PhD Research Fellow at the University of Eastern Finland. Where are you from? I am from Pakistan, raised in Middle East and currently doing my PhD in Finland. What is your field of neuroscience? Why did you choose it? I am investigating molecular changes in brain after traumatic brain injury. I always wanted to explore the central nervous system, and how it effects the rest of the body. I believed that our brain makes us who we are! Plus I really enjoy microscopy and brain cells put up a great show under the lens! 😀 What do you want to share with students aiming to pursue a career in neuroscience too? Neuroscience is exciting and challenging. There are wonders hidden in complexity of brain. I believe that commitment to your goals and professionalism is an asset. Additionally, efficient planning, time management and good documentation leads to a successful project, irrespective of the field of work.
Heading to Barstow this weekend with my friends for the @thelightsfest so I thought I’d share one of the cooler fossils from the area here at the @alfpaleo museum! Behold the 15 million year old camel footprints found right in the deserts of Barstow. Here you can see two sets of tracks made by two camels walking side by side. Measuring the tracks shows us that the camels were probably moving at a paving gait, which is where an animal moves both limbs on the same side of the body at the same time. Walking this way creates a very straight path and is super efficient energy wise when traveling long distances. No other animal except the modern camel has this kind of style of walking today! PS. The camel skeleton in the background is Ned the Camel. Ned is a modern camel skeleton and not the camel that made these tracks. We have Ned there to show the size difference modern camels and their extinct relatives. Oh! And awesome fact! Camels first evolved in North America and then spread out to the rest of the world! #fossilfriday #fossilsofinstagram #footprints #barstow #camels #naturalhistorymuseum #claremont #thescicommunity #filipinoscientist
Great news, folks! My first article is up with the American Association for the Advancement of Science (@aaasorg ) for their Public Engagement Reflections blog. Couldn’t be more hyped to share this news. Learn about my experiences with public speaking (link in bio👉) Big shout out to @thescalex.of.science for sharing the opportunity! Can you tell how excited I am from the number of exclamation marks I’m using??!!!
Happier than I look ◼️🙂
Hi SciCommunity members! I want to introduce you to my initiative, The Social Scientist (@thesocscientist ) and (thesocialscientist.org). The idea behind this are the many issues we face trying to connect with other science professionals. What I think our field is missing are people who can give a complete view of their work, environment and what it took for them to get here. Instead of cold calling or trying blindly to have individuals respond to your messaging, these contacts (in various scientific positions) are readily available and willing to speak on their experiences and advice. Specifically, this would provide contacts to science professionals that want to help others in order to create an engaging yet open scientific community. We want to support everyone from high school students to associate professors passionate about science. This initiative would provide a chance to have an informal call with science professionals to talk about their specific position, the route they took to get to their position, their general field, atmosphere, surrounding area and any general questions. Chat with one of our awesome volunteers today! If you are a science professional interested in joining the initiative, you can contact Danielle @dltomasello !
"People form themselves in dialogue" - Anne Carson. . Imagine we invented a device that holds the potential to record/transmit our memories, dreams, and ideas to someone else. Sounds mind-blowing right? Like a game-changing technology from the future? I don’t think so… we already possess this extraordinary tool called human communication. . In my previous post, I talked about why storytelling is useful in science communication. How about we take a closer look at how our brains connect during this process? . Research has identified the factor that enables us to convey a story. It's a hidden neural protocol called neural entrainment, the capacity of our brain to synchronize patterns. Normally brain activity patterns are completely random and different in a resting state. However, if we listen to the same story, we see that our patterns in the auditory cortex, which processes incoming sound, are becoming synced. . This alignment already becomes visible with just random sounds. However, if we complicate the message (words -> sentences -> story) the area in our brain in which the patterns align becomes larger. When we hear a captivating story, even regions like the frontal & parietal cortex, show alignment. This is because the speaker also conveys meaning rather than just some sentences. . What is even more fascinating is that not only the brain patterns of people listening to a story align but also those of the speaker & listener. The stronger the alignment between the two, the better the communication. In order to achieve this, speaker & listener need to have a common ground, feeling of understanding, and shared beliefs. . This is why knowing your audience is so important in scicomm and communication in general. If you don’t, your story might be completely misunderstood. People who share a different belief system actually showcase different brain patterns when exposed to the same story. . How can we counter this in an age where so many external factors influence our belief systems? Return to the natural way of communicating: dialogue. Find a common ground and new ideas together by talking and listening. In the end, the people we are coupled to define who we are.
If you’re around next Tuesday 5-6pm don’t forget to stop by for some mulled wine, minced pies and a dose of caffeine. Again we’ll be in the student common room Of the Old Medical School. We’ll make sure to take Last Christmas off the playlist to make sure you survive Whamageddon. Please RSVP (link in Bio) so we know how many to cater for, make sure to take a break from exam period!
I’m a bit of a silly nut sometimes, but nothing helps clean your filthy keyboard (anything for that matter) better than a good spray of Ethanol. Can’t believe it’s been a year since I started my journey onto this PhD... Pray to the science lords we make it through the winter and second year! ✨🎄
Its friday! And we’ve officially finished our first week of summer here in Australia! As I mentioned in my last post, I got out in the sun for a bush walk yesterday, and down to the beach today (swipe left) as part of my “me time” 🤙🏼 But as its starts to get hotter, the more people start to flock to the beach! And Australia isn’t called the sunburnt country for nothing! A lot of foreigners are still so surprised by how easily they get sunburnt when they visit here. And the skin cancer rates are ridiculously high here in australia 😔 (about 1 in 24 males and 1 in 34 for females are at risk of developing melanoma before the age of 75) So a science and geography lesson if you’re going to jump out into the sun this summer in Australia: 🤓 The ozone layer (a part of the earth’s stratosphere that absorbs most of the UV radiation from the sun) is much thinner over Australia than, say Europe, due to Australia’s proximity to Antarctica where there is an ozone hole. The presence of this ozone hole means that more UV radiation reaches earth, thus making it much more likely that you’re going to get sunburnt! (Dont worry, I’m not going to go into the chemistry behind the formation of the ozone hole) ☀️ Additionally, compared to Europe, during summer Australia, earth’s orbit brings it closer to the sun which means we get approximately 7% higher UV intensity! 🌏 Don’t forget though, genetics also plays a role in your susceptibility to sunburn and skin cancer. If you’re family and ancestors are from areas where the ozone layer is thicker (eg anglo/celtic/european), your skin is much more poorly adapted to the harsh conditions here in Australia than indigenous peoples! So if you’re out in the sun this summer don’t forget to slip slop slap! 😎 (Slip on a 👕 , slop on some 🧴 , and slap on a 🧢)
Welcome to Pharmacology Friday: Herbal Holidays! Each December post will explore a commonly used plant compound, and the evidence (or lack thereof) for its efficacy. First up: ginseng! Multiple ginseng subtypes have been employed by traditional medicine for several millennia. The best studied of these is Panax ginseng (Korean ginseng). There is limited (and conflicting) evidence of its clinical efficacy, but it is clear that ginseng is a highly biologically active plant. The pharmacologically active component of ginseng is a steroid glycoside called ginsenoside. At least 40 ginsensoides have been isolated from Korean ginseng, which are named alphabetically according to increasing chromatographic polarity prefixed with the letter R for root (i.e. Ra, Rb etc.). The range of active ginsenosides found in ginseng most likely explains its wide range of biological activity. Such effects include increased plasma concentration of luteinizing hormone, glial cell-derived neurotrophic factor and testosterone, as well as agonism of steroid hormone receptors, including oestrogen and glucocorticoid. There is weak evidence of some ginsenosides inhibiting the breakdown of acetylcholine, as well as modulating serotonin receptors. There is fairly strong evidence of ginseng’s antioxidant activity. However, the oral bioavailability of ginseng is poor, and the dosage given in over-the-counter supplements is unlikely to have any effect. The main problem with the available evidence of ginseng’s efficacy is the tendency for studies to lack robustness and statistical rigour, and be published in niche journals. Unlike many herbal medicines, ginseng appears to have a low risk of toxicity, but side effects include abdominal discomfort and insomnia. Ginseng can interact with some antidepressants and anticonvulsants so should not be taken with these. It may also cause liver damage when taken alongside some cancer drugs, which is important as ginseng is often peddled (alongside other herbs) by quacks to desperate patients as an effective cancer treatment (IT IS NOT). As with all herbal supplements, it is important to inform your GP/pharmacist if you take ginseng!
Today's look... a little OTT for the lab, but this is my first successful cut crease 👏🏻 baby steps 💁🏼‍♀️
#BrainyXmas day 6 🎄🧠: Katherine (@grad_selfcare ) battling mental illness with her coolness! 1. Who are you? Where are you from? Hi! I’m Katherine, a 4th year Neuroscience PhD candidate at the University of Illinois at Urbana-Champaign. In addition to grad school, I’m an avid reader, podcast listener, and beer drinker. Because of my battle with mental illness and poor mental health, I was inspired to start my self-care and mental health awareness account/blog @grad_selfcare. 3. What is your field of Neuroscience? Why did you choose it? My research is kind of all over the place, so I’ll refer to myself as a Neurotoxicologist. But I’m also a Chronobiologist and Neuroendocrinologist hopeful. I’m currently studying how environmental exposures impact the brain and behavior. But in the long run, I’m interested in studying the biological basis of circadian disruption and it’s negative impact on health. 4. What do you want to share with students aiming to pursue a career in Neuroscience? Diversify your undergraduate, postundergrad, and graduate school experiences! Don’t focus too hard on one problem, or one skill. Follow and balance ALL of your passions, both in and out of the lab. I did a lot more than just research in undergrad and postundergrad, and I think that the skills I learned outside of the lab were just as, if not more, important than those learned in the lab. Teach, give presentations, mentor, volunteer, get a job before grad school... there are so many ways to diversify your skill set!
SCIENCE SNIPPET: Ash tree populations could be spared from Ash Tree Dieback. - Ash Tree Dieback, or Hymenoscyphus fraxineus , has been spreading throughout Europe for the past twenty years, devastating ash tree populations throughout the continent, around 70% in forested areas. H. fraxineus is a fungal disease that infects trees, causing leaf necrosis and lesions to form, eventually leading to the tree’s death. - However, small numbers of ash trees are surviving the epidemic, and it’s hoped that these individuals are genetically more resilient than others, potentially leading to a stock of trees that can survive infection. - Dutch elm disease has been equally devastating to Elm tree species over the past century, and some progress has been made in developing resistant cultivars.
Yesterday I showed you guys the seahorse machine. So today I thought I’d explain the data we get from it 👩🏼‍🔬📈! ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ The seahorse measures the oxygen consumption rate (OCR) of live cells - giving you an indicator of mitochondrial respiration. To do this we plate cells into a 96 well cell culture plate, which is then inserted into the seahorse analyser. The baseline OCR (pmoles/min) is measured first, before the addition of three inhibitors which are preloaded into drug delivery ports above the cell culture plate and injected sequentially into each well. ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ The first of these inhibitors; oligomycin is an ATP synthase inhibitor 🚫, which stops the electron transport chain and consequently inhibits oxidative phosphorylation. You can see from the graph above how the OCR decreases after the injection of oligomycin. ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ The second inhibitor; FCCP is a mitochondrial uncoupler, which works by transporting H+ ions ⬇️ across the inner mitochondrial membrane. This collapses the mitochondrial membrane potential and leads to the consumption of oxygen and energy without producing ATP so gives a read out of the maximal respiration and the cells spare respiratory capacity. ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ And finally; rotenone and antimycin A, which block ❌ complexes I and III of the electron transport chain and subsequently eradicates mitochondrial respiration - allowing you to calculate the levels of non-mitochondrial respiration.
It’s been a crazy last 2 weeks and it’s not over yet . I am heading to crawley again next week for work and my Mind is stuffed with work , things to be done before I head off , things that can wait until after I come back , omg My Son And his packing so that his father doesn’t go crazy finding things for him while I am away( although I have a top feeling that I am going to get calls asking where are the nappies ,where are his socks ,what do I pack for his lunch , where is his water bottle , does he drink whole milk or skimmed ? Is he allowed pizza 🍕...you get the idea ) I am overwhelmed .. This my second trip away from my little unicorn but this time I am more confident and less worried ( does that make me horrible mother - I mean what the heck ) ... The holidays are going to be busy for me with work and I don’t have a moment to stop ! In next few weeks I have huge decisions to make and I am nervous to the core . But here is what I am going to do ! . I am going to #breath . I am going to slow down and focus on work at hand . Don’t mind me but I am going to go ahead say I am a fabulous mother and leaving my son home so I go away for work is totally acceptable ( and those who judge can go F*** themselves ) . I am going to master the decision making based on what I want to do not what my circumstances dictate ( it’s now or never) . I am going to forget about cleaning and I will eat out of freezer and I will watch another Netflix series without regrets . . I don’t care about next years goals because I know I am going to make a difference in whatever little or more I do . . I am not going to lose it instead I will practice patience . . I got this 😀( ask me next week if I really got this 😂) . . Are you all feeling it ? What’s going on in your marvellous brains ? . I will post more work related life next week when I am doing some work on linear accelerators ! . Have you got any questions for me ? DM Me or write in the comments ! . . . #yougotthis #stemgoals #workmode #momlife #toddlermom #physics #science #scientist #lifeofascientist @thestemsquad #thescicommunity #scicomm #thescientist @thescicommunity #letitgo #radiationphysics
✨Fun fact Thursday✨: Do you know why sky is blue 💙, clouds white ☁️ and grass green 🌱 ? Do you think black is a color? 🤔 . . . I used to ask adults questions like these all the time growing up, but it was physics that started answering them all. ☺️ If you happen not to know the answers, read the text below 👇 The Sun’s rays contain all the color of the rainbow 🌈 mixed together. This mix is known as white light. When light shines on an object some colors bounce off and some get absorbed. Our eyes see the colors that bounce of objects. 😄 So for example, when light shines on a plant all the colors get absorbed except for color green. . . . Now, Sun releases billion of photons and it takes them 8 min and 17s for them to reach Earth. 🌍 On their way to Earth some photons get absorbed by atmosphere and that is exactly why we see sky as blue. Basically, some of the blue light (because blue light has the shortest wavelength) is bounced off more than other colors of the rainbow and during the day when we look up we see all that that blue light! 😀💙 And when light hits clouds instead, all the light gets reflected down to Earth so clouds seem white to us. ☁️🙂 . . . In short, this mixture of color (white light), when bounces off, all the 🌈 colors object seems white, because it absorbs no color and reflects all colors equally. When object absorbs all colors except, for example, red we will see red color. And if the object absorbs all the colors object seems black because it doesn’t reflect (bounces off any color). So while artists will say that black is a color, scientist will claim that black is actually absence of color. 🖤 What is your answer now - is black a color or maybe absence of all colors? ——————————————— #womeninstem #instascience #physicsgirl #physics #nerdgirl #womenwhoscience #scicomm #girlswhoscience #phdstudent #phdlife #stem #studentlife #phd #womendoingscience #thescicommunity #shecanstem #studyphysics #womenempowerment #liverpool #scientistswhoselfie #scicomm #sciencefacts #coolscience #funfacts #sciencenews #scienceisawesome #einstein #blogerka #nauka #color
We believe in the power of hands-on learning and expanding kids’ horizons, so they can think differently and feel confident tackling tough problems! That is why we are proud to support @cisfsailing which encourages the next generation to become ocean and environmental champions. Congratulations to CISF on a powerful year of marine programming! To learn more about the organization's work, click on the link in our bio. 📷 @cisfsailing
Extracellular Flux Analyzer ... ⠀⠀⠀⠀⠀⠀⠀⠀⠀ a.k.a the seahorse 🌊🐴 ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ This machine measures cell metabolism!
#BrainyXmas day 5🎄🧠: Today is all about the brainSTEM, inflammation, and breathing! . Hey everyone! 🖖 I'm Vanesa (@neurosciencewithness ) & I'm a Postdoctoral Scientist with a combined major in Neuroscience and Immunology. My research is all about helping preterm babies 👶 breathe at birth! I study how inflammation during pregnancy affects the nerves in the fetal and neonatal brainstem which controls our breathing The brainstem is the critical control centre for many vital bodily functions - and breathing is one of them! So the fact that many babies are unable to breathe at birth makes me suspect that there's something going on in the brainstem! And it's my job to find out what! For anyone wishing to pursue a career in neuroscience/science - it's a very rewarding career choice! I love being in the lab making new discoveries! And I love being able to see the world in a different light! But just remember that science can be very challenging! You will experience a lot of failures (experiments) and rejections (publications/applications) But try your best to work strategically/smart, surround yourself with a positive and supportive network of people, and most importantly - don't forget to take care of yourself! 😊
PrEP (Pre-Exposure Prophylaxis) is a method for people who do not have HIV but who are at high risk of getting it to prevent HIV infection. This method involves taking a pill (Brand name: Truvada) every day. It contains two medicines (tenofovir and emtricitabine) that are used in combination with other preventive strategies to treat HIV. If the person taking the pill consistently is exposed to HIV through sex or use of infected needles, these medicines can work to keep the virus from establishing a permanent infection. PrEP is a powerful HIV prevention tool and can be combined with condoms and other prevention methods to provide even greater protection than when used alone. It has been shown to reduce the risk of HIV infection in people who are at high risk by up to 92%. Studies have shown that PrEP reduces the risk of getting HIV from sex by more than 90% when used consistently. Among people who inject drugs, PrEP reduces the risk of getting HIV by more than 70% when used consistently. Firstly, you need to know your HIV status by taking an HIV test. On the basis of your test results, you can talk to a well informed health care provider to know if PrEP is the right HIV prevention strategy for you. The key thing is to know that if PrEP is prescribed, you must commit to take the drug every day and see you health care provider for follow-up every 3 months. PrEP can cause side effects like nausea in some people, but these generally subside over time. No serious side effects have been observed, and these side effects aren’t life threatening. If you are taking PrEP, tell your health care provider about any side effects that are severe or do not go away. But remember this way is only for people who are at ongoing very high risk of HIV infection. #HIV #AIDS #science #study #scicomm #sciencelife #scicommer #thescicommunity #biology #health #healthcare #medicine #who #cdc #illness #infection #disease #awareness #lab #research #endAIDS #microbiology #pathology
How cute is this bookworm from @giantmicrobes 😭 Anobium punctatum is also known as the common furniture beetle, but it is the larvae that are referred to colloquially as the bookworm. A. punctatum larvae spend around five years eating their way through wood (including bookcases) as well as the pages of old books! . . . . . science #stem #phdlife #lablife #pharmacology #biochemistry #phd #scientist #toxicology #womeninstem #scicomm #sciencecommunication #academia #discoverunder10k #postgrad #womeninscience #scientistsofinstagram #thescicommunity #bookworm #beetle #giantmicrobes
Between work and uni applications I feel I’ve been going a bit stir crazy lately. Since my next due date isn’t for a while, I’m taking the next two days to relax and pursue some hobbies. Its been quite a few years since I’ve picked up a pencil and paper and I forgot how fun it was to create stuff! Of course i then had to go and fit some gaming in and destroy some stuff to balance it out 🎮 😉 Fingers crossed the weather is nice tomorrow so I can do another favourite hobby of mine: bushwalking 🏃🏽‍♀️🌳 Have you taken some personal time lately? What are your hobbies? 👩🏼‍🎨👩🏼‍🏭🤺🏋🏼‍♀️🏊🏼‍♂️
SCIENCE SNIPPET: What exactly is the Trump effect? - Having bad hair? A miniaturisation of the hands? - No, it’s the impact that Trump politic has on other nations and organisations, particularly with regards to climate change. Former President Barack Obama signed the Paris Agreement back in 2016, a multilateral agreement between all signatory parties to limit the global temperature increase to less than 2C. In 2017, President Donald Trump began the process to withdraw from the agreement, citing economic disadvantages. - This was not without impact. Following the U.S. signing up to the agreement, investment in fossil fuels by American banks dropped by 38%. However, after President Trump was sworn in, investments increased by 6%. Brazil, Australia, Turkey and Russia have all dialled back their response to the climate change crisis, creating a widespread belief that governments are not committed to combating climate change. - Ironically, President Trump stated that he was ‘elected to represent the citizens’ of Pittsburgh, not Paris’. In turn, the mayor of Pittsburgh redoubled efforts to reduce its greenhouse gas emissions.
Tissue sections stained with insulin... do you know what tissue this is and what cells produce insulin❓ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ *hint* I posted a similar post last week!
#BrainyXmas 4 🧠🎄: Today it’s Ellen’s turn, who is investigating the memory circuit with the help of electrophysiology! Hi! My name is Ellen (@rescuesrescueme ), and I am PhD candidate at the University of Michigan. I am an electrophysiologist in circuits neuroscience. I study how neurons connect and talk to one another in a memory circuit in the brain. I chose this work for two reasons: 1) Once learned, slice electrophysiology gives immediate gratification - you see how the neuron is behaving in real time, so there’s no waiting like in molecular neuroscience. (Plus I get to eavesdrop on neurons’ conversations, and I just think that’s really cool.) 2) My work is largely exploratory - we don’t know what’s going on in this circuit or even what types of neurons are in these brain regions, so every day is new and exciting. I started with a hypothesis-driven project, but I got bored pretty quickly because I just needed to increase my sample size (n), repeating the same things over and over and knowing what I was going to see each time. So I changed my entire dissertation focus at the end of my 2nd year to something that was extremely interesting and a total mystery. Now, I get to have a lot more fun collecting all these puzzle pieces of data and trying to fit them together to see the big picture. My advice for someone aiming to pursue a career in neuroscience is to try a lot of different things, both research-related and otherwise. I started in undergrad administering assessment batteries to human subjects, then running fMRI scans on college students, then using optogenetics in epileptic rats, then in grad school I moved to inducing seizures in slices, engaging in science communication events with the public, and finally, I’ve landed on studying cortical circuits involved in memory. I learned all of the things I enjoy (electrophysiology in vitro, giving presentations, writing) and all of the things I despised (animal surgeries, molecular assays, most lab work). Neuroscience is an amazingly cool and wonderful thing, but it’s also difficult and demanding. [read more ⬇️⬇️⬇️]
✨Fun fact Tuesday✨: What if I told you that, in theory, if you run really really fast you would gain weight? 😳🤔 . . . Ok... to be completely honest, you would only gain tiny amount for a short period of time but still... 😄 . . . 👇 Here is the explanation 👇 Speed of light is the speed limit of the universe. If something travels with speed close to the speed of light and you give it additional push. You can’t make that object go much faster. However, you gave that object additional energy and that energy has to go somewhere. The place it goes is mass. 🙂 . . . Now, you might have seen this formula before E=mc^2. It is probably most famous physics equation. What this equation says is that mass (m) and energy (E) are equivalent. You can actually think of mass and energy as different forms of the same thing. “C” in the equation is speed of light and that can not increase, right? So when you increase the energy mass increases as well. 😊 . . . Of course, at human speed this is negligible otherwise all those diets and exercise plans would be for nothing. 😉 ——————————————————————- #womeninstem #instascience #physicsgirl #physics #nerdgirl #womenwhoscience #scicomm #girlswhoscience #phdstudent #phdlife #stem #studentlife #phd #womendoingscience #thescicommunity #shecanstem #studyphysics #womenempowerment #liverpool #scientistswhoselfie #scicomm #sciencefacts #coolscience #funfacts #sciencenews #scienceisawesome #einstein #blogerka #nauka #elementi
Yesterday’s blood isolation 💉
“Failure is just a normal part of the academic career path” – dr. Melanie Stefan. . You certainly have a few versions of your CV, each supplemented with new successes. But what about a CV of failure? In 2010, Dr. Melanie Stefan, now lecturer at Edinburgh Medical School: Biomedical Sciences, mentioned the idea in the Journal Nature. Let’s ask her about it. . Q: How did you come up with the idea of building a CV of failure? . A: I like following sports, especially football. It struck me that failures in professional sports are immediately visible and discussed by a wide audience, whereas failures in academia are usually kept hidden and not discussed at all. I thought it would be helpful to be more open about failures to show that it is just a normal part of the academic career path. . Q: How can a CV of failure help scientists? . A: Personally, it has helped me understand that I am not the only one who fails, and that even the most successful colleagues have had moments of rejection. I also hope it makes successful senior scientists reflect on their own history, and encourages junior colleagues who face difficult times. . Q: Do you keep updating your own CV of failure? Do you still agree with your idea from 2010? . A: I have kind off been neglecting my CV of failures. There are just too many to keep track of! But I do keep a list of rejected grant applications so I can go back and learn from them. Also, my thinking has evolved, thanks to conversations I have had with others. Many pointed out that "CVs of failure" presuppose a position of power & privilege. A lot of great scientists who fail early on don't have support structures (networks, money, institutional support, etc.) to keep trying until they succeed. So, reading about other people's early failures and later successes might actually be discouraging instead of helpful. The other thing is that we need to have a talk about what "failure" & "success" even mean. In academia, we have a narrow view of success and we measure it using very specific, yet arbitrary metrics. But there are different ways of being successful, and therefore different views on what failure is. . [Image: profile pic of dr. Melanie Stefan]
Grad school applications; If you don’t feel at least a little bit narcissistic after writing multiple, are you even doing them right? 😭😂 So you may have noticed I’ve been a bit MIA on here lately, and as you can probably guess, its because I’ve been writing up applications for grad school. I’m about half way through my submissions now and boyyyy am I sick about talking about myself. 😂 For all of you going through the same motions at the moment, I feel you! But don’t worry we’ve got this, and if you don’t get in, its not the end of the world! My 3 top tips I’ve found are: 1. Start early (and I mean AT LEAST 3-6 months before they are due) and don’t forget funding which is often done much earlier 2. Get yourself some good references 3. Get as much feedback as possible on your applications, and also on your school/program choices from people currently there Do you have any other tips? Or questions regarding applications? Or experiences to share so I don’t feel so alone? 😉 Happy to do some more in depth discussions on my process for applying and experiences 😊
Welcome to the first post of Toxicology Tuesday’s Christmas Toxins Series! Nutmeg adds a delicious flavour to Christmas dinner and desserts, but be careful not to eat too much… In quantities that are typically added to recipes, this spice is totally safe, so season away. However, large doses of freshly ground nutmeg (or nutmeg oil) can be toxic, and three fatal overdoses have been documented. This is due to the neurotoxic effects of two phenylpropene compounds it contains: elemicin and myristicin (pictured). Both compounds are found in a number of plant essential oils, and if enough is ingested they will inhibit acetylcholine (Ach) receptors in the nervous system (have you noticed yet that this is a prime target for toxins?). This contributes to the main symptoms seen in nutmeg poisoning: hallucinations, paranoia, nausea, convulsions and dehydration. These may take several hours to appear. But wait, there’s more! Myristicin also (weakly) inhibits monoamine oxidase, an enzyme family responsible for the breakdown of monoamine neurotransmitters (and as the name suggests, the target of the monoamine oxidase inhibitor (MAOI) class of antidepressants). As well as this, myristicin is also a commonly employed precursor in the synthesis of MMDA* (a structural analogue of MDMA). With this combination of mechanisms, it’s no wonder that nutmeg overdose can result in hectic psychosis. Treatment involves fluid therapy, monitoring of cardiac and respiratory activity and, in cases of severe psychosis and anxiety, sedation with benzodiazepines. Nutmeg should be avoided during pregnancy, and kept out of reach of children and pets. . . *Please do not try to synthesise MMDA this Christmas. . . . . . #science #stem #phdlife #lablife #pharmacology #biochemistry #phd #scientist #toxicology #womeninstem #scicomm #sciencecommunication #academia #discoverunder10k #postgrad #womeninscience #scientistsofinstagram #thescicommunity #toxicologytuesday #christmas #nutmeg #toxins #festive #poison #essentialoils
If you’re a scientist communicating your science, you’ll probably be creating things to help with that: a presentation, a poster, a video, a podcast, etc. 📽️ But in that video, poster, presentation, etc., what happens if you really need to incorporate material that was created by someone else? For example, you might really like to include someone’s else image in your presentation or another’s recording in your video. 🖼️ Unfortunately, the rules of traditional copyright heavily frown upon just using someone else’s stuff without permission. Lucky for you though, there is a class of copyright license – called Creative Commons – which encourages reuse and remixing of content. Even better, there is an unending supply of Creative Commons-licensed material just waiting for you to use. Images, audio, video - you name it, Creative Commons has got your back (case in point: the image used for this post!). Want to know more about where to find Creative Commons material? Follow the link in our bio! 📷 . . #scifund #scicomm #creativecommons #freeart #sciencecommunication #communication #themoreyouknow #scicommtips #science #scienceeducation #stem #stemed #sciencerules #sciencerocks #thescicommunity #storytelling #instascience
👩🏼‍🔬 ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀ Think it’s time to tidy the lab bench 🙈
#BrainyXmas - day 3 🧠🎄 . Q: Who are you? A: Hey! Sammi Howard (@sammihow ) here. I'm a Neuroscience PhD Student at Tufts University School of Medicine in Boston, Massachusetts. I'm originally from Cupertino, California --> went to undergraduate in Los Angeles --> then ventured out east for graduate school. Q: What is your field of neuroscience? A: My field is the neural circuitry of energy balance. I'm curious as to how a key population of hypothalamic neurons regulates whole-body energy and glucose homeostasis. 🍫⚖️Understanding how dysfunction in these neurons contributes to metabolic and neurodegenerative diseases is critical for identifying new/effective brain-based therapeutic targets. Q: Why did you choose it? A: I chose this specific field due to my fascination with the brain's role in homeostasis - or the ability to maintain biological function at a set point throughout the changes that occur throughout everyday life such as learning, development, growth, and experiences. I was specifically drawn to general neuroscience due to the appeal of the unknown and the vast space for discovery. So many people are affected by neurological disorders yet effective treatment is severely lacking! I was also greatly inspired by books such as "The Brain That Changes Itself" by Norman Doidge which touch on the plastic/ homeostatic mysteries of the brain. Q: What do you want to share with students aiming to pursue a career in neuroscience? A: A PhD is like a marathon so find a question that gets you excited and it will feel more like fun than work! Also, be sure to prioritize mental and physical health. I have found my morning routine of either running or CrossFit incredibly helpful! I relish those few hours I set aside for myself to find clarity and motivation to take on the day. Lastly, the field of neuroscience is interdisciplinary and rapidly progressing. Keep an open-mind and expose yourself to novel ideas outside your niche field. Attend conferences/meet-ups, get on social media (neuro twitter community rocks!), and read journals. You never know what inspiration you can find through expanding your neuro realm!
⚠️Adoptive cell transfer by @t.cell.sarah ⚠️ _________________________________________________ What is adoptive cell transfer and why should we care about it❓. . Personalised medicine and immunotherapy 💉🧬are quickly being adopted into a clinical setting especially in cancer treatment. . But what is adoptive cell transfer? It’s an exciting therapy, where immune cells are isolated from the patient’s blood and expanded to very high numbers 🧫. The cells can also be modified to help with the tumour killing ☠. Once expanded in culture, the cells are then injected back into the patient💉, this could be one single injection or multiple shots depending on the treatment💊. . Adoptive cell transfer is not a new concept and has been around since 1960 👴🏼, where lymphocytes were discovered to be mediators of allograft rejection in animals 🐷. This led to lymphocytes being transferred from rodents 🐁 heavily immunised against the tumour to inhibit growth of small established tumours. . More recently, CAR T-cells are being used to target cancer cells📍. T cells are good at fighting infection but sometimes it can be difficult for them to tell the difference between a cancer cell and a normal cell 🤔. In CAR T-cell therapy, T cells are taken from the patient 😷 and in the lab, the T cells are genetically engineered 🧬 to recognise and target specific proteins expressed by cancer cells 😈. The CAR T-cells are then injected back into the patient’s body and, because of the changes made, they can stay in your body for long periods of time ⏳, recognising and attacking specific cancer cells. . Research into CAR T-cell therapy is still very new 🔬 and side effects and long-term risks are still unknown 🧐, however these new types of T cells are providing some very promising results in cancer therapies 🥳. _________________________________________________ 📸: 1. Tissue culture set up for my T cells and below T cells forming clumps (circled in blue), 2. Flow cytometry analysis of T cells and 3. Me! 😊 _________________________________________________ Please, let's thank Sarah for such an interesting and informative post, and let us know your feelings about CAR T-cell therapy⬇️
Exactly my type of Christmas tree this year! 🎄🥰
Happy first work day of December friends 👬. To kick off the Christmas 🎄 season, we present an animation of twinkling ✨ root cells responding to treatment with the neurotransmitter glutamate. The root shown here harbors a genetically- encoded calcium biosensor called GCAMP3. When calcium goes up, light released (false colored as red) by the biosensor goes up. . Glutamate was applied to the root at about the 1 min mark. Within seconds, one can see bursts of Christmas red propagating toward the tip of the growing root. . Like many organisms, plants 🌱 decode these rapid and transient cellular calcium changes into specific growth responses.
“Storytelling is the most powerful way to put ideas into the world today” – Robert McKee.📖 . Telling stories has always been part of being a human. It is one of our most important social bonding mechanisms. Telling a good story is an art. 🙏 It has the power to engage, influence, teach and inspire those on the receiving end. It is through storytelling that we can ensure that scientific facts become part of the shared knowledge that drives the very possibility of scientific progress. A narrative offers increased comprehension, interest and engagement and can therefore increase the uptake and validation of scientific results within the community. But what is the science behind storytelling?🤔 . When we present our scientific facts in the format of a captivating story, that is expressive in character and rich in detail, something incredible happens. Both the language parts of our brain🧠 (Broca’s and Wernicke’s area) as well as the parts that we would actually use when we would experience the story in real life are activated⚡️. We literally immerse ourselves in the story and engage with it. If we don’t tell a story only the language parts are activated, resulting in our brain designing a story of its own which might not be the same as the one the speaker tries to convey.☝️ . Also chemicals like cortisol, dopamine and oxytocin are set free in our brain when we hear a story. 👂 Cortisol helps us formulate memories, dopamine keeps us engaged and oxytocin is an important element in building deepening relationships. . To end, one of the most important aspects of storytelling is that it is essential in meaning and sense making. It provides us with the opportunity to better understand the world around us as well as challenge and expand our own understanding by exploring the views of others. By sharing and listening to one another, we get a little bit closer to the truth. And isn’t that what being a scientist is all about?😁 . Do you use storytelling in your science communication or professional life?😁 And who do you know is an excellent storyteller. Tag them down below.
HIV continues to be a major global public health issue, having claimed more than 35 million lives so far. HIV is a virus that spreads through certain body fluids and attacks the body’s immune system. If left untreated, HIV reduces the number of CD4 cells (T cells) in the body. This damage to the immune system makes it very hard for the body to fight off infections. Opportunistic infections /cancers take advantage of a very weak immune system and signal that the person has AIDS. The only way to know for sure whether you have HIV is to get tested. There are three types of tests available: nucleic acid tests (NAT), antigen/antibody tests, and rapid antibody tests. They are mostly performed on blood and oral fluid. Only certain body fluids—blood, semen, pre-seminal fluid, rectal fluids, vaginal fluids, and breast milk—from a person who has HIV can transmit HIV. These fluids must come in contact with a mucous membrane or damaged tissue or be directly injected into the bloodstream (from a needle or syringe) for transmission to occur. Preventative strategies include abstinence (not having sex), limiting your number of sexual partners, never sharing needles, and using condoms the right way every time you have sex. You can also take advantage of newer HIV prevention medicines such as pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP). If you are living with HIV, there are many ways to prevent passing it to others. The most important is to take antiretroviral therapy each day, the right way. Remember, HIV is NOT transmitted by Air, Water, saliva, tears, sweat, insects, pets, closed mouth kissing, sharing food and water. #cdc #who #health #biology #science #scicomm #sciencelife #research #thescicommunity #scicommer #STEM #HIV #AIDS #medicine #awareness #endAIDS #disease #microbiology #pathology #illness #lab #loveforscience #infection
Ministry of Science in Montenegro endorsed my #cern related blog by sharing it on their Facebook page! They encouraged people applying for CERN summer student program to use it! 💙 I know I am spamming you here with Tau Bytes but I am so, so, so happy about this project. It already helped students and reactions on Thomas’s book are amazing! 🥰🥰🥰 I worked hard to make it useful, helpful and inspiring. I truly hope I managed to achieve my goal and that future posts will keep being as helpful and inspiring as previous ones. 😊 P.S. If you have any suggestions for CAREER and PEOPLE section of the blog please write an email on mail@taubytes.com (you can suggest yourself if you think your story is worth sharing 😉). Thanks and wish you a happy and productive week! 😘😘😘 ———————————————————————— #blog #scienceblog #scienceblogger #cernblog #taubytes #livbloggers #womeninstem #instascience #physicsgirl #nerdgirl #womenwhoscience #scicomm #girlswhoscience #phdstudent #phdlife #stem #studentlife #phd #womendoingscience #shecanstem #womenempowerment #cern #girlboss #coolscience #sciencenews #scienceisawesome #liverpoolbloggers #thescicommunity #helpstudents #sciblog
When you accidentally match your nails to the vacutainers 💅🏻
Over the Horizon The coutdown for the last year of PhD is about to start. Now is time to prepare plans for thr future. Great things to have some real good friends I can allways relay on! Becuase when is the moment to take bif decisions are those that can really help to clarify your vision and desires. They make you see over the horizon. Over the Horizon is actually a techinical term. It is refered to the capability of electromagnetic waves in the microwave range to be transmitted for very long distances, "over the horizon" (20 Km), as the stratosphere can act as a waveguide, like an optical fiber for your high-speed internet connection. This was first proven by Guiglielmo Marconi in December 1901, setting the base for the development of radio and radar technologies. #friends #bestfriend #radio #invention #perseverance #knowwhoyouare #resilient #beyourbestself #noordinarylife #scicomm #coutdown #deadline #innovation #decisions #shoulders #fit #sciencelife #inspiration #stem #research #physics #engineerlife #lovescience #sciencegeek #instascience #scienceworld #phdlife #phd #physics #thescicommunity
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