Y’all ever have this happen?
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How are ya'll?
2 minutes ago
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Sunday stretch with
@livingminnaly 😍
Stretching can help to improve blood flow, relieve stress and calm your mind ahead of the week ahead 🙌
3 minutes ago
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✨Estrogens role in endometriosis pain
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It is known that endometriosis is an estrogen dependent disease, and that estrogen has a central role in the progression of endometriosis, however, the exact mechanism of endometriosis related pain is unknown. There is recent evidence that estrogen plays a pivotal role in the maintenance of endometriosis related pain
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It has been shown that estrogen levels are higher in women with endometriosis within the menstrual blood and within the peritoneal fluids
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Estrogen increases the expression of nociceptors (sensory receptor for pain) on peripheral nerves which leads to local inflammation
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Estrogen also promotes the secretion of inflammatory cytokines from macrophages, which are molecules excreted from immune cells that promote inflammation. Macrophages are one of the most numerous immune cells in endometriotic lesions and the amount of macrophages are significantly higher in peritoneal fluid of women with endometriosis
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This impairment of the immune environment within the peritoneal cavity induces inflammation which in turn leads to an increase in endometriosis related pain. (Yanchun, 2018)
3 minutes ago
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